This is the toughest stage of the Tirreno-Adriatico Crédit Agricole featuring an uphill finish. It winds its way along the valleys of the Marche hinterland, rising and falling non-stop in the first part, and taking in some major climbs such as the Forchetta di Valle Avellana and the ascent of Pian di Trebbio. On the slopes of Monte Petrano, the peloton will negotiate the short, steep climb of Moria (about 2.5 km at 9%) to reach Cagli where the final ascent begins.
The final kilometres correspond to the climb to Monte Petrano. At 10.1 km in length and an average gradient of 8.1%, the climb rises steeply in the first kilometres (up to 12%), and with constant grades in the second part, with numerous hairpins. When approaching the summit plateau, the gradient decreases.